The Impact of Space and Time on the Functional Output of the Genome
Marcello Nollmann, Isma Bennabi, Markus Götz, and Thomas Gregor (2021). Cold Spring Harb Perspect Biol.: a040378. doi: 10.1101/cshperspect.a040378.
(more…)Author Archive
Trading bits in the readout from a genetic network
Marianne Bauer, Mariela D Petkova, Thomas Gregor, Eric F Wieschaus, William Bialek (2021). Proceedings of the National Academy of Science 118 (46): e2109011118.
The many bits of positional information
Gašper Tkačik and Thomas Gregor. Development 148: dev176065 (2021) (more…)
Using RNA Tags for Multicolor Live Imaging of Chromatin Loci and Transcription in Drosophila Embryos
Chen H and Gregor T. In: Heinlein M. (eds) RNA Tagging. Methods in Molecular Biology, vol 2166. Humana, New York, NY (2020). (more…)
Eco-evolutionary significance of “loners”
Fernando W. Rossine, Ricardo Martinez-Garcia, Allyson E. Sgro, Thomas Gregor, Corina E. Tarnita. Eco-evolutionary significance of “loners”. PLoS Biol 18(3): e3000642 (2020). (more…)
Optimal decoding of cellular identities in a genetic network
Mariela D. Petkova, Gasper Tkacik, William Bialek, Eric F. Wieschaus, and Thomas Gregor. Cell 176(4), 844–855 (2019). (more…)
Diverse spatial expression patterns emerge from unified kinetics of transcriptional bursting
Benjamin Zoller, Shawn C. Little, and Thomas Gregor. Cell 175(3), 835–847 (2018). (more…)
Dynamic interplay between enhancer-promoter topology and gene activity
Hongtao Chen, Michal Levo, Lev Barinov, Miki Fujioka, James B. Jaynes and Thomas Gregor. Nature Genetics 50, 1296–1303 (2018). (more…)
Single mRNA Molecule Detection in Drosophila
Shawn C Little and Thomas Gregor. In: Gaspar I. (eds) RNA Detection. Methods in Molecular Biology, vol 1649. Humana Press, New York, NY (2018) (more…)
Live Imaging of mRNA Synthesis in Drosophila
Hernan G Garcia and Thomas Gregor. In: Gaspar I. (eds) RNA Detection. Methods in Molecular Biology, vol 1649. Humana Press, New York, NY (2018) (more…)
Beyond D’Arcy Thompson: Future challenges for quantitative biology
Thomas Gregor. Mechanisms of Development 145: 10–12 (2017). (more…)
Only accessible information is useful: insights from gradient-mediated patterning
Mikhail Tikhonov, Shawn C. Little, and Thomas Gregor. Roy. Soc. Open Sci. 2: 150486 (2015). (more…)
Enhancer additivity and non-additivity are determined by enhancer strength in the Drosophila embryo
Jacques Bothma, Hernan Garcia, Samuel Ng, Michael W. Perry, Thomas Gregor, and Michael S. Levine. eLife 2015; 4:e07956 (2015). (more…)
Modeling oscillations and spiral waves in Dictyostelium populations
Javad Noorbakhsh, David J. Schwab, Allyson E. Sgro, Thomas Gregor, and Pankaj Mehta. Physical Review E 91: 062711 (2015). (more…)
From Intracellular Signaling to Population Oscillations: Bridging Size and Time Scales in Collective Behavior
Allyson E. Sgro, David J. Schwab, Javad Noorbakhsh, Troy Mestler, Pankaj Mehta, and Thomas Gregor. Molecular Systems Biology 11: 799 (2015). 
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Positional information, positional error, and read-out precision in morphogenesis: a mathematical framework
Gasper Tkačik, Julien O. Dubuis, Mariela D. Petkova, and Thomas Gregor. Genetics 199 (1): 39–59 (2015). (more…)
The embryo as a laboratory: quantifying transcription in Drosophila
Thomas Gregor, Hernan G. Garcia, Shawn C. Little. Trends in Genetics 30 (8): 364–375 (2014).
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Dynamic Regulation of Eve Stripe 2 Expression Reveals Transcriptional Bursts in Living Drosophila Embryos
Jacques P. Bothma, Hernan G. Garcia, Emilia Esposito, Gavin Schlissel, Thomas Gregor, Michael S. Levine. PNAS 111 (29): 10598–10603 (2014).
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Fly wing vein patterns have spatial reproducibility of a single cell
Laurent Abouchar, Mariela D. Petkova, Cynthia R. Steinhardt, and Thomas Gregor. J. Roy. Soc. Interface 11 (97): 20140443 (2014).
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Lots of November Press for TGLab
“Seeing the Pattern”
Nature Reviews Genetics (PDF)
“Measuring Transcription to Follow Embryo Development”
BioTechniques News Highlight
“Scientist to watch: Thomas Gregor – Biological Quantifier”
The Scientist
“Development: Lights, Camera, Action — The Drosophila Embryo Goes Live!”
Current Biology Dispatch by Bothma and Levine (PDF)
“Nature – the IT wizard”
Nautilus Magazine