Laboratory for the Physics of Life Thomas Gregor, Professor of Physics, Princeton University

We are currently looking for postdoctoral candidates interested in the following three general themes:

1. At the level of a genetic network, extract global properties and design principles from expression level measurements and analysis.

2. At the molecular level, develop mathematical models underlying the fundamental mechanisms of transcriptional regulation and test these using single molecule and live measurements of the transcriptional output.

3. At the level of the dynamics of the DNA polymer, link the nuclear architecture with actual transcriptional activity in terms of multiple enhancers recruiting the same promoter in a given cell.

Experimental and theoretical physicists (preferentially with experience in biological and/or soft-matter physics), engineers and materials scientists with experience in biology, and biologists interested and experienced in quantitative approaches are strongly encouraged to apply. Outstanding applicants in other fields (mathematics, computer science, chemistry, etc.) may also be considered. Experience with microscopy and image analysis is a plus.

Applicants should email me their CV and a brief description of research interests, as well as their motivation to join the lab.

Marcello Nollmann, Isma Bennabi, Markus Götz, and Thomas Gregor (2021). Cold Spring Harb Perspect Biol.: a040378. doi: 10.1101/cshperspect.a040378.

Marianne Bauer, Mariela D Petkova, Thomas Gregor, Eric F Wieschaus, William Bialek (2021). Proceedings of the National Academy of Science 118 (46): e2109011118.

Gašper Tkačik and Thomas Gregor. Development 148: dev176065 (2021) (more…)

Chen H and Gregor T. In: Heinlein M. (eds) RNA Tagging. Methods in Molecular Biology, vol 2166. Humana, New York, NY (2020). (more…)

Fernando W. Rossine, Ricardo Martinez-Garcia, Allyson E. Sgro, Thomas Gregor, Corina E. Tarnita. Eco-evolutionary significance of “loners”. PLoS Biol 18(3): e3000642 (2020). (more…)

Mariela D. Petkova, Gasper Tkacik, William Bialek, Eric F. Wieschaus, and Thomas Gregor. Cell 176(4), 844–855 (2019). (more…)

Benjamin Zoller, Shawn C. Little, and Thomas Gregor. Cell 175(3), 835–847 (2018). (more…)

Hongtao Chen, Michal Levo, Lev Barinov, Miki Fujioka, James B. Jaynes and Thomas Gregor. Nature Genetics 50, 1296–1303 (2018). (more…)

Shawn C Little and Thomas Gregor. In: Gaspar I. (eds) RNA Detection. Methods in Molecular Biology, vol 1649. Humana Press, New York, NY (2018) (more…)

Hernan G Garcia and Thomas Gregor. In: Gaspar I. (eds) RNA Detection. Methods in Molecular Biology, vol 1649. Humana Press, New York, NY (2018) (more…)

Thomas Gregor. Mechanisms of Development 145: 10–12 (2017). (more…)

Mikhail Tikhonov, Shawn C. Little, and Thomas Gregor. Roy. Soc. Open Sci. 2: 150486 (2015). (more…)

Allyson E. Sgro, David J. Schwab, Javad Noorbakhsh, Troy Mestler, Pankaj Mehta, and Thomas Gregor. Molecular Systems Biology 11: 799 (2015).  (more…)

Gasper Tkačik, Julien O. Dubuis, Mariela D. Petkova, and Thomas Gregor. Genetics 199 (1): 39–59 (2015).  (more…)

Thomas Gregor, Hernan G. Garcia, Shawn C. Little. Trends in Genetics 30 (8): 364–375 (2014).
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Jacques P. Bothma, Hernan G. Garcia, Emilia Esposito, Gavin Schlissel, Thomas Gregor, Michael S. Levine. PNAS 111 (29): 10598–10603 (2014).
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Laurent Abouchar, Mariela D. Petkova, Cynthia R. Steinhardt, and Thomas Gregor.  J. Roy. Soc. Interface 11 (97): 20140443 (2014).
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