Posts Tagged ‘gene regulatory networks’

Precise and scalable self-organization in mammalian pseudo-embryos

Mélody Merle, Leah Friedman, Corinne Chureau, Armin Shoushtarizadeh & Thomas Gregor.
Nature Structural & Molecular Biology, doi: 10.1038/s41594-024-01251-4 (2024)

Functional analysis of the Drosophila eve locus in response to non-canonical combinations of gap gene expression levels

Netta Haroush, Michal Levo, Eric Wieschaus, Thomas Gregor. Developmental Cell 58 (23), 2789-2801.e5 (2023).

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Eukaryotic gene regulation at equilibrium, or non?

Benjamin Zoller, Thomas Gregor, and Gasper Tkacik. Current Opinion in System Biology 31: 100435 (2022).

Latent space of a small genetic network: Geometry of dynamics and information

Rabea Seyboldt, Juliette Lavoie, Adrien Henry, Jules Vanaret, Mariela D. Petkova, Thomas Gregor, and Paul François. Proceedings of the National Academy of Science 119 (26): e2113651119 (2022).

Trading bits in the readout from a genetic network

Marianne Bauer, Mariela D Petkova, Thomas Gregor, Eric F Wieschaus, William Bialek (2021). Proceedings of the National Academy of Science 118 (46): e2109011118.

The many bits of positional information

Gašper Tkačik and Thomas Gregor. Development 148: dev176065 (2021) (more…)

Optimal decoding of cellular identities in a genetic network

Mariela D. Petkova, Gasper Tkacik, William Bialek, Eric F. Wieschaus, and Thomas Gregor. Cell 176(4), 844–855 (2019). (more…)

Only accessible information is useful: insights from gradient-mediated patterning

Mikhail Tikhonov, Shawn C. Little, and Thomas Gregor. Roy. Soc. Open Sci. 2: 150486 (2015). (more…)

Positional information, positional error, and read-out precision in morphogenesis: a mathematical framework

Gasper Tkačik, Julien O. Dubuis, Mariela D. Petkova, and Thomas Gregor. Genetics 199 (1): 39–59 (2015).  (more…)

The embryo as a laboratory: quantifying transcription in Drosophila

Thomas Gregor, Hernan G. Garcia, Shawn C. Little. Trends in Genetics 30 (8): 364–375 (2014).
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Morphogenesis at criticality

Dmitry Krotov, Julien O. Dubuis, Thomas Gregor, and William Bialek. PNAS 111 (10): 3683–3688 (2014).
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Positional information, in bits

Julien O. Dubuis, Gasper Tkacik, Eric F. Wieschaus, Thomas Gregor and William Bialek, PNAS 110, 16301-16308 (2013).
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Precise developmental gene expression arises from globally stochastic transcriptional activity

Shawn C. Little, Mikhail Tikhonov and Thomas Gregor, Cell 154, 789–800 (2013).
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Dynamic interpretation of maternal inputs by the Drosophila segmentation gene network

Feng Liu, Alexander H. Morrison and Thomas Gregor, PNAS 110: 6724–6729 (2013).
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