Posts Tagged ‘gene regulatory networks’

Finding the last bits of positional information

Lauren McGough, Helena Casademunt, Miloš Nikolić, Zoe Aridor, Mariela D. Petkova, Thomas Gregor.
PRX Life 2 (1), 013016 (2024)

Precise and scalable self-organization in mammalian pseudo-embryos

Mélody Merle, Leah Friedman, Corinne Chureau, Armin Shoushtarizadeh & Thomas Gregor.
Nature Structural & Molecular Biology, doi: 10.1038/s41594-024-01251-4 (2024)

Functional analysis of the Drosophila eve locus in response to non-canonical combinations of gap gene expression levels

Netta Haroush, Michal Levo, Eric Wieschaus, Thomas Gregor. Developmental Cell 58 (23), 2789-2801.e5 (2023).


Eukaryotic gene regulation at equilibrium, or non?

Benjamin Zoller, Thomas Gregor, and Gasper Tkacik. Current Opinion in System Biology 31: 100435 (2022).

Latent space of a small genetic network: Geometry of dynamics and information

Rabea Seyboldt, Juliette Lavoie, Adrien Henry, Jules Vanaret, Mariela D. Petkova, Thomas Gregor, and Paul François. Proceedings of the National Academy of Science 119 (26): e2113651119 (2022).

Trading bits in the readout from a genetic network

Marianne Bauer, Mariela D Petkova, Thomas Gregor, Eric F Wieschaus, William Bialek (2021). Proceedings of the National Academy of Science 118 (46): e2109011118.

The many bits of positional information

Gašper Tkačik and Thomas Gregor. Development 148: dev176065 (2021) (more…)

Optimal decoding of cellular identities in a genetic network

Mariela D. Petkova, Gasper Tkacik, William Bialek, Eric F. Wieschaus, and Thomas Gregor. Cell 176(4), 844–855 (2019). (more…)

Only accessible information is useful: insights from gradient-mediated patterning

Mikhail Tikhonov, Shawn C. Little, and Thomas Gregor. Roy. Soc. Open Sci. 2: 150486 (2015). (more…)

Positional information, positional error, and read-out precision in morphogenesis: a mathematical framework

Gasper Tkačik, Julien O. Dubuis, Mariela D. Petkova, and Thomas Gregor. Genetics 199 (1): 39–59 (2015).  (more…)

The embryo as a laboratory: quantifying transcription in Drosophila

Thomas Gregor, Hernan G. Garcia, Shawn C. Little. Trends in Genetics 30 (8): 364–375 (2014).

Morphogenesis at criticality

Dmitry Krotov, Julien O. Dubuis, Thomas Gregor, and William Bialek. PNAS 111 (10): 3683–3688 (2014).

Positional information, in bits

Julien O. Dubuis, Gasper Tkacik, Eric F. Wieschaus, Thomas Gregor and William Bialek, PNAS 110, 16301-16308 (2013).

Precise developmental gene expression arises from globally stochastic transcriptional activity

Shawn C. Little, Mikhail Tikhonov and Thomas Gregor, Cell 154, 789–800 (2013).

Dynamic interpretation of maternal inputs by the Drosophila segmentation gene network

Feng Liu, Alexander H. Morrison and Thomas Gregor, PNAS 110: 6724–6729 (2013).