A conserved coupling of transcriptional ON and OFF periods underlies bursting dynamics
Po-Ta Chen, Michal Levo, Benjamin Zoller, Thomas Gregor. Nature Struct Mol Biol (2025). DOI: 10.1038/s41594-025-01615-4
(more…)Posts Tagged ‘gap genes’
Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation
Anand P. Singh, Ping Wu, Sergey Ryabichko, Joao Raimundo, Michael Swan, Eric Wieschaus,
Thomas Gregor, and Jared E. Toettcher (2022). Cell Reports 38, 110543.
Positional information, positional error, and read-out precision in morphogenesis: a mathematical framework
Gasper Tkačik, Julien O. Dubuis, Mariela D. Petkova, and Thomas Gregor. Genetics 199 (1): 39–59 (2015). (more…)
Morphogenesis at criticality
Dmitry Krotov, Julien O. Dubuis, Thomas Gregor, and William Bialek. PNAS 111 (10): 3683–3688 (2014).
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Positional information, in bits
Julien O. Dubuis, Gasper Tkacik, Eric F. Wieschaus, Thomas Gregor and William Bialek, PNAS 110, 16301-16308 (2013).
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Precise developmental gene expression arises from globally stochastic transcriptional activity
Shawn C. Little, Mikhail Tikhonov and Thomas Gregor, Cell 154, 789–800 (2013).
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Dynamic interpretation of maternal inputs by the Drosophila segmentation gene network
Feng Liu, Alexander H. Morrison and Thomas Gregor, PNAS 110: 6724–6729 (2013).
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Accurate measurements of dynamics and reproducibility in small genetic networks
Julien O. Dubuis, Reba Samanta and Thomas Gregor, Molecular Systems Biology 9: 639 (2013).
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