Laboratory for the Physics of Life Thomas Gregor, Professor of Physics, Princeton University

“Seeing the Pattern”
Nature Reviews Genetics (PDF)

“Measuring Transcription to Follow Embryo Development”
BioTechniques News Highlight

“Scientist to watch: Thomas Gregor – Biological Quantifier”
The Scientist

“Development: Lights, Camera, Action — The Drosophila Embryo Goes Live!”
Current Biology Dispatch by Bothma and Levine (PDF)

“Nature – the IT wizard”
Nautilus Magazine

Mariela D. Petkova, Shawn C. Little, Feng Liu, and Thomas Gregor. Current Biology 24 (11): 1283–1288 (2014).
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Dmitry Krotov, Julien O. Dubuis, Thomas Gregor, and William Bialek. PNAS 111 (10): 3683–3688 (2014).
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Hernan G. Garcia, Mikhail Tikhonov, Albert Lin and Thomas Gregor. Current Biology 23, 2140–2145 (2013).
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Laurent Abouchar, Mariela D. Petkova, Cynthia R. Steinhardt, and Thomas Gregor (2013).  arXiv.org:1309.6273 [q-bio.TO].
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Julien O. Dubuis, Gasper Tkacik, Eric F. Wieschaus, Thomas Gregor and William Bialek, PNAS 110, 16301-16308 (2013).
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Shawn C. Little, Mikhail Tikhonov and Thomas Gregor, Cell 154, 789–800 (2013).
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Feng Liu, Alexander H. Morrison and Thomas Gregor, PNAS 110: 6724–6729 (2013).
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Julien O. Dubuis, Reba Samanta and Thomas Gregor, Molecular Systems Biology 9: 639 (2013).
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Alexander H. Morrison, Martin Scheeler Julien O. Dubuis and Thomas Gregor, Cold Spring Harb Protoc. 2012(4): 398-406 (2012).
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PLoS Press Release for our first paper on mRNA quantification in whole embryos.

“How are biologic molecules arranged inside the embryo so that embryonic development occurs reliably every time? Princeton researchers, led by Thomas Gregor, an assistant professor of physics and the Lewis-Sigler Institute for Integrative Genomics, and Shawn Little, a postdoctoral fellow in the laboratory of Professor Eric Wieschaus in the Department of Molecular Biology, have developed a new method to better understand how an embryo’s basic molecular makeup helps ensure that the embryo’s development occurs reliably every time. The results of this research into the fruit fly Drosophila introduce a method for making precise measurements of biologic units (so-called mRNA molecules) that play a key role in development. The findings are published in the March 1st issue of  in the online, open access journal PLoS Biology.”

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Shawn Little, Gašper Tkačik, Thomas Kneeland, Eric Wieschaus and Thomas Gregor, PLoS Biology 9(3): e1000596 (2011).
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G. Tkačik, T. Gregor, W. Bialek, PLoS One 3, e2774 (2008).

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T. Gregor, W. Bialek, R. R. deRuyter van Steveninck, D. W. Tank, E. F. Wieschaus, PNAS 102, 18403-18407 (2005).

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